Best Bioinformatics Software for Startups

We build products with our in-house chemists, biologists and clients to deliver outstanding performance and scientific understanding. Chemaxon offers a wide range of products, including out-of-the box solutions for scientists and IT professionals. It also includes components that add extra functionality as well as integrations with 3rd-party software, such Microsoft Excel or KNIME. Chemaxon, a leading software provider, is trusted by more than one million users. Its industry-leading tools for scientific discovery include calculation, search, and drawing tools. Our applications are used widely in education and research in the life sciences. Our clients come from a wide range of industries. The majority of major pharmaceutical companies are among them. Our offices are located at Budapest, Basel and Boston, with distributors all over the world.

Pluto was founded in 2021 by the Wyss Institute of Harvard University. It has been a trusted partner for many life sciences organizations across the country, from biotech start-ups and public biopharma companies. Our cloud-based platform allows scientists to manage all their data, run bioinformatics analysis, and create interactive visualizations that are published-quality. The platform is being used for a variety of biological applications. These include preclinical and translational science research, cell and gene therapies and drug discovery and development.

OmicsBox, a leading bioinformatics tool, offers end-toend data analysis for genomes, transcriptomes and metagenomes. It also provides genetic variation studies. The application, which is used by leading private and public research institutes worldwide, allows researchers to process large and complicated data sets and streamline their analytical process. It is designed to be efficient, user-friendly and equipped with powerful tools to extract biological insight from omics data. The software is divided into modules, each of which has a set of tools and features designed to perform specific types of analyses, such as de novo genome assemblies, genetic variations analysis, differential expression analyses, taxonomic classifications, and taxonomic classes of microbiome, including the interpretation of results and rich visualizations. The functional analysis module uses the popular Blast2GO annotating methodology, making OmicsBox a great tool for non-model organisms research.

g6gTech Inc. is a software company that develops deep search products in the fields of bioinformatics (AI) and artificial intelligence (AI). To emphasize our focus on creating products, we have changed our name from G6G Consulting Group. The new G6GFINDR System, powered by semantic annotation, searches an expanding database bioinformatics software and artificial intelligence software. It uses a two-step process to allow you to refine your search. The previously developed Directory of Omics, Intelligent Software was used as a starting point. We are expanding our database of searched products at a rapid pace. All products in the database were carefully selected. To optimize results, the G6GFINDR system uses cookies to automatically gather information about your activities. g6gTech Inc. created the G6GFINDR system.

Ruffus is a Python computation pipeline library. It is open-sourced and powerful, user-friendly, and widely used for science and bioinformatics. Ruffus was designed to automate scientific and other analyses with minimal fuss and effort. It is suitable for even the most basic tasks. Even complex pipelines can be handled. This will prevent make or scons from becoming cross-eyed and recursive. No "clever magic", no pre-processing. The lightweight syntax, which does one small thing well, is unambitious. Ruffus is licensed under the permissive MIT-free software license. This license allows for free use and inclusion in proprietary software. It is a good idea to run your pipeline in a temporary directory that is not connected to your original data. Ruffus is a lightweight Python module that can be used to build computational pipelines. Ruffus requires Python 2.6 and higher, or Python 3.0 and higher.

Geneious Prime makes bioinformatics more accessible by transforming raw information into visualizations which make sequence analysis intuitive. Simple assembly of sequences and easy editing contigs. Automatic annotation of gene prediction, motifs and translation. Genotype microsatellite trace with automated ladder fitting, peak calling, and generation of tables of alleles. A highly customizable sequence view displays beautiful visualizations of annotated assemblies and genomes. SNP variants analysis with powerful SNPs, RNA-Seq analysis and amplicon metagenomics. Create your own searchable database of primers, test PCR and sequence primers, and design and test them. CRISPR tools are powerful and make it easy to analyze your editing results, find sites, and design guide RNAs. Pre-processing NGS data with extensive tools for downstream analysis produces clean sequences. Create phylogenetic tree using peer-reviewed algorithms.

Qlucore Omics Explorer makes it so simple to use that you don't have to rely on a specialist in bioinformatics for analysis and exploration of your Omics or NGS data sets. Qlucore Omics Explorer, a next-generation D.I.Y bioinformatics software, is available for research in academia, life science, and plant-tech industries. The flexible and powerful visualization-based data analysis tool delivers instant results and allows for the exploration and visualization of large data. The software was designed to allow you to choose the best workflow for your experiments and maximize the results of your research. You will be able see your results instantly by combining instant visualization with powerful statistics, flexible selection methods, and powerful statistics. You decide the workflow and starting point for your own exploration. You have complete control over the exploration process and can tailor it to your needs.

Founded in order to improve lives through high-value care, the hc1 platform has become a leader in bioinformatics for precision prescribing and testing. The cloud-based hc1 high-value care platform® organizes large amounts of live data, including genomics and medications, to provide solutions that ensure the right patient receives the right test and prescription. The hc1 Platform is a platform that powers solutions that optimize diagnostic testing, prescribing, and patient care for millions of patients across the country. Visit www.hc1.com to learn more about the proven approach of hc1 to personalizing care and eliminating waste for thousands upon thousands of health systems, diagnostic labs, and health plans.

Universal Analysis Software (UAS), a platform that analyzes and manages forensic genomic data, simplifies complex bioinformatics. The UAS is an all-inclusive solution that includes analysis modules for all ForenSeq workflows, including ForenSeq MainstAY and ForenSeq Kintelligence. It also contains ForenSeq DNA Signature prep, ForenSeq DNA Whole Genome, ForenSeq Control Region, ForenSeq mtDNA Whole Genome and ForenSeq UAS Control Region. UAS quickly generates FASTQ files and performs alignment. It also calls forensically relevant variants using NGS data. The extensive testing behind UAS's variant calls ensures that they are reliable and deliver accurate results in a user-friendly package that does not require per-seat licenses. UAS is a tool for forensic analysts. It streamlines the handling of base-bybase sequence information. It also includes a variety of features that allow you to perform everything from a quick review of everyday STR profiles to detailed analysis on the most difficult samples.

Legacy R&D software can be a drain on scientific potential. It slows down R&D progress and scatters data between silos. Benchling is the industry's most trusted life sciences R&D cloud. All the tools you need to accelerate, measure, and forecast R&D, from discovery through bioprocessing, all in one place. A suite of seven applications that are natively unified and can be used to accelerate R&D at all levels. Open integration, codeless configuration, and dashboards that are tailored to your needs. For continued success, deep life science R&D and consulting expertise are essential. Benchling is a unified R&D platform that allows you to spend less time searching for data and more time working together in order to advance your research. Scientists, managers, executives, and researchers can optimize R&D output by having complete visibility into the experimental context, program performance, resource utilization, and program performance.

The QIAGEN CLC Geneomics Workbench is a powerful tool that works for all workflows. It is easy to overcome data analysis challenges with cutting-edge technology, unique features and algorithms that are widely used by scientists in industry and academia. Bioinformatics software solutions that are user-friendly allow for comprehensive analysis and interpretation of your NGS data. This includes de novo assembly and transcriptome assembly, resequencing analysis, WES and targeted panel support, variant calling, variant calling, RNA–seq, ChIP–seq and DNA methylation analysis (bisulfite sequence analysis). You can analyze your RNA-seq (miRNA, smallRNA) and smallRNA (lncRNA), data using easy-to-use transcriptomics workflows that allow for differential expression analysis at both gene and transcript levels. QIAGEN CLC Genomics Workbench was designed to support a wide variety of NGS bioinformatics programs.

Partek bioinformatics software provides powerful visualization and statistical tools in an intuitive interface. Researchers of all levels can explore genomic data faster and more efficiently than ever before. We turn data into discovery®. Our intuitive interface makes it easy for scientists to perform sophisticated array and NGS analysis using pre-installed workflows. Public and custom statistical algorithms can be used together to quickly and accurately distill NGS data into biological insights. Genome browser, Venn diagrams and heat maps, as well as other interactive visualizations, show the biology of your next generation sequencing and array data in vivid color. Our Ph.D. scientists can be reached at any time to assist with your NGS analysis. This product is specifically designed for next-generation sequencing applications that require high-level computing. It offers flexible installation and management options.

Correlation Engine, an interactive omics database, places private omics data into a biological context by combining it with highly curated publicly available data. Correlation Engine, one of the largest databases in the world for life science research, provides researchers with unprecedented access and insight to a vast number of high-quality whole genome analyses. The knowledgebase allows for novel discoveries through the interrogation of billions of datapoints derived from standard analyses of whole genome studies. A suite of applications for determining biological context, a constantly growing library of curated datasets, and support of multiple species and multi-omic data sets. Use a simple graphical interface to leverage guided workflows and APIs. Accelerate the journey from omic to decision-making and gain access to more than 25,000 multi-omics studies that have been reanalyzed (from over 250.000 signatures).

Emedgene streamlines tertiary analyses for germline research and rare disease genomics. Emedgene was designed to speed up the time and certainty of user-defined variant interpretations, prioritizations, curations, and research reports. Automate your tertiary analyses with explainable AI and automation that supports genomes, exomes and virtual panels. Unify your NGS instruments and your IT systems in order to simplify and secure the entire workflow. With the latest knowledge graph options, curation abilities, and a team to support you, you can confidently keep up with evolving science, technologies, and demand. Automated workflows and explainable AI (XAI), which can be used to increase throughput without adding more staff, are a great way to do this. Implement a high-throughput WGS,WES, virtual panel or targeted panel workflow integrated into your lab's ecosystem.

Store, archive, and manage multi-omic data sets. Illumina Connected Analytics provides a secure platform for genomic data to operationalize informatics, and drive scientific insight. CWL and Nextflow allow you to easily import, build and edit workflows. Leverage DRAGEN bioinformatics pipelines. Organize your data in a safe workspace and share it with the world in a compliant way. Our platform allows you to keep your data in the cloud. Visualize and interpret data using a flexible analysis tool, such as JupyterLab Notebooks. Data warehouses allow you to aggregate, query and analyze sample data and population data. Scale analysis operations through the creation, validation, automation, and deployment of informatics pipelines. Reduce the time needed to analyze genomic data when quick results are a key factor. Enable comprehensive profiling for the identification of novel drug targets and biomarkers of drug response. Data can be transferred seamlessly from Illumina sequencing platforms.

Illumina DRAGEN Secondary Analysis is a comprehensive and accurate analysis of next-generation sequence data. Machine learning and graph reference genome drive unprecedented accuracy. Ultra-efficient workflow. Can process a whole 34x human genome in under 30 minutes using DRAGEN server version 4. Reduces FASTQ files up to 5x, resulting in an ultra-efficient workflow. Analyzes data from next-generation sequencing (NGS), including whole genomes, transcriptomes, methylomes and exomes. Available on the platform of your choice and scalable according to needs. DRAGEN analysis is the most accurate for germline and somatic mutation calling, as demonstrated by precisionFDA's industry challenges. DRAGEN analysis allows labs of any size and discipline to do more with genomic data. DRAGEN analysis is based on highly reconfigurable FPGA technology to provide hardware-accelerated implementations for genomic analysis algorithms.

Data management and simplified Bioinformatics are ideal for labs that are just getting started or for those who want to scale up their next-generation sequencing operations quickly. BaseSpace Sequence hub is an integral part of the BaseSpace Suite and is a direct extension to your Illumina instruments. BaseSpace Sequence hub allows you to manage your data with ease using a set of curated analysis apps. BaseSpace Sequence hub is powered by Amazon Web Services. Provides a secure environment. You can set up runs and monitor the quality of instrument runs. By converting sequence data into a standard format, and streaming it directly to the cloud, this tool promotes efficiency. Access to computing resources is available without the need for capital expenditures. Access to a variety of genomic analysis apps, whether provided by you, Illumina or third parties, increases organizational productivity.

Microsoft's experience and scale in managing exabyte-scale workloads can be used to reduce the need for you to manage your own data center. Microsoft Genomics on Azure gives you the performance and scalability that comes with a supercomputing facility of the highest caliber, all on demand. Take advantage of an MPI backend network that has a latency of under three microseconds, and a non-blocking throughput of 32 gigabits per seconds (Gbps). This backend network features remote direct memory access, which allows parallel applications to scale up to thousands of cores. Azure offers high memory and HPC class CPUs to help get results quickly. Scale up or down according to your needs and only pay for what you actually use. Azure's worldwide network of data centers can help you meet your compliance needs and address data sovereignty issues. Easy integration into your existing pipeline code with a REST API and simple Python client.

GenomeStudio Software allows you to visualize and analyze data from Illumina array platforms. This powerful tool supports genotyping analysis of microarray datasets. Performance-optimized tools and a user-friendly graphical interface enable you to convert data into meaningful results quickly and easily. Analyze SNP/CNV data across 5,000,000 probes and markers. Detect outliers in sample data. Analyze differentially expressed genes across multiple genomes. Profile miRNA expression. Combine microRNA and mRNA data into one project. Single-base resolution detection of cytosine methylation. Identify methylation signatures throughout the entire genome. Illumina's goal is to use innovative technologies to analyze genetic variation and function. This will allow us to do studies that were impossible just a few short years ago. We believe it is vital to provide innovative, flexible, and scalable solutions that meet the needs of customers.

Polly allows you to harness the power of biomedical information. The Polly Platform allows you to scale batch jobs, workflows and visualization applications. Polly supports resource pooling, optimizes resource allocation based upon your usage requirements, and makes use of spot instances when possible. This results in optimization, efficiency, quicker response time, and lower costs for resources. Access a dashboard that allows you to monitor and track resource usage and costs in real-time. This will allow you to reduce overheads when resource management is done by your IT team. Polly's infrastructure is built around version control. Polly uses a combination dockers and interactive notebooks to ensure version control for your analyses and workflows. We have created a mechanism that allows data, code, and the environment to co-exist. This, along with cloud data storage and the ability for users to share projects, ensures reproducibility in every analysis.

A robust platform for automatic variant prioritization and clinical interpretation, as well as report generation, is essential to ensure efficient reporting of NGS-based clinical trials. Strand Omics, a cloud-based platform that is HIPAA-compliant and fast, drives our clinical diagnostics practice. It has been refined over 4 years with over 10,000 clinical reports and multiple peer reviewed publications. Strand Omics is a combination of bioinformatics algorithms and curated databases, visualization interfaces, and reporting capabilities. It offers specialized workflows that can be used for rare inherited disorders and somatic tumor profiling tests. The platform has over 10,000 variants curated to oncogenicity, 100 genes that are curated for druggability across multiple types of cancer, and 500 drugs that have been curated for evidence.

ESP is a unified, composable, and bimodal platform with a single data fabric that reduces the total cost of operations while enabling digital transformation for life sciences + healthcare. This FDA-compliant platform includes a number of best-in-class apps, including ELN, LIMS and Sample Management. ESP's REST API library and Python SDK enable flexibility and extensibility to meet customer-specific requirements. Each release is constantly updated with new applications. ESP ships with a wide range of pre-built connectors to lab Instruments, bio-process equipment, analytics, AI/ML, 3rd party software systems (such as ERP, CRM, EMR, etc.) logistics systems, bar-code printers, etc.

Eidogen-Sertanty’s Target Informatics platform (TIP), is the first global structural informatics system. It enables researchers to examine the druggable genome from an structural perspective. TIP increases the rapidly expanding body experimental protein structure information and transforms structure based drug discovery from an inefficient, data-scarce discipline to a high-throughput science with rich data. TIP is a tool that bridges the knowledge gap between bioinformatics (bioinformatics) and cheminformatics. It provides drug discovery researchers with a knowledge bank of information that is both unique and highly complementary to existing bio- and cheminformatics platform information. TIP's seamless integration between structural data management technology and unique target-to-lead analysis capabilities enhances every stage of the discovery pipeline.

Stop messing around with broken informatics tools and cloud infrastructure. Get started today on uncovering biological insights. Scientists are often limited by the fragmentation of tools across biology and bioinformatics teams. To help teams accelerate their R&D, we created a harmonized platform for bioinformatics between the cloud and the wet lab. Import raw data from your cloud service provider, your team's instruments, or your cloud. Create and deploy custom bioinformatics workflows using any language. Stop wasting time tinkering with your infrastructure. You can easily run any workflow and keep track of every analysis. Interactive visualizations of NGS data ready-to-go with point-and click plots Latch integrates with your AWS S3. You can access hundreds of terabytes in organic filesystems you are familiar with. Create bioinformatics workflows, and dynamically create no-code interfaces with Python with tunable storage and compute.

Swiss-PdbViewer, also known as DeepView, is an application that allows you to analyze multiple proteins simultaneously. To compare active sites and other parts, the proteins can be superimposed. The intuitive interface and graphic make it easy to find information about amino acid mutations, Hbonds, angles and distances between atoms. Nicolas Guex has been developing Swiss-PdbViewer (aka DeepView), since 1994. Swiss-PdbViewer was originally tightly connected to SWISS-MODEL (an automated homology modeling server) that was developed at the Structural Bioinformatics Group of the Biozentrum in Basel. The SWISS-MODEL interface has evolved to the point that advanced modeling can now be done directly. It is no longer possible to maintain a direct interface with SwissPdbViewer.